Effects and Benefits of HHC

Hexahydrocannabinol, or HHC, is a minor cannabinoid considered a semisynthetic compound. It is naturally found in low quantities in hemp, inadequate for commercial extraction. That is why manufacturers make HHC via hydrogenation of either THC or CBD. 

To date, we know little about HHC due to insufficient research. Hence, we have to rely upon anecdotal evidence to explain the effect, benefits, and risk factors associated with the compound.  

Effects of HHC

Experts believe the effect of HHC on the body might be comparable to that of THC. They argue that, like THC, HHC also interacts with CB1 and CB2 receptors of the endocannabinoid system. The prime difference between them lies in their potencies; anecdotal evidence shows that HHC produces less high than THC. It reaches your bloodstream when you consume HHC via ingesting or smoking, from where it is transported to the brain. There, it binds with the endocannabinoid system, which then stimulates alteration in emotions, appetite, mood, and perception, getting you high. It is worth mentioning that, like other cannabinoids, the effect of HHC is not the same for everyone. Therefore, you might feel a different sensation than what you expect. Additionally, some people might have to face more adverse effects. Nonetheless, nonscientific evidence tells that it will still reduce the symptoms of chronic pain, insomnia, and other health conditions.

Benefits of HHC

As we have established earlier, almost every information about HHC is anecdotal. Scientists are still trying to explore the newly famous cannabinoid, so we have to bank on the experience shared by various HHC users. Here are some possible health advantages of HHC, as reported by consumers and small scientific studies.

HHC Might Boost Appetite

If you search benefits of HHC on google, you will find this one repeatedly. It is because there is strong anecdotal evidence that HHC is instrumental in increasing your hunger. Therefore, it might be advantageous for those who have lost their appetite.

HHC Might reduce Pain and Inflammation

An animal study in Japan in 2007 shows that HHC might help reduce chronic pain. The study revealed that HHC interacts with CB1 receptors that might generate specific signals associated with reducing inflammation and pain alleviation.

HHC Might Help induce sleep

Many HHC consumers claim that it induces sleep. There are two arguments to support their claim; the resemblance of HHC with delta-9 in its sedative effect and its interaction with CB1 receptors in the endocannabinoid system. It is believed that ECS might have a say in controlling sleep-related neurotransmitters.

HHC Might Reduce Anxiety

There is substantial anecdotal evidence that hexahydrocannabinol might help treat symptoms related to anxiety, depression, and mood swings. Although no conclusive scientific research proves its anxiolytic property, consumers report feeling relieved after using HHC. The effect might be linked to its structural similarity with delta-9 tetrahydrocannabinol and the fact that it also binds to the same receptors.

HHC Might Reduce Tumor Growth

The potential of natural and synthetic cannabinoids to fight and reduce tumor cell growth has been the subject of numerous scientific studies. After discovering HHC and its similarity to other cannabinoids, experts believe it might also be effective as an anti-tumor cannabinoid. As published by National Center for Biotechnology Information (NCBI), a hexahydrocannabinol analog LYR-8 might inhibit tumor growth.


Effects and benefits of HHC are largely not scientifically proven as the substance is relatively new on the market. Since hexahydrocannabinol has similarities to THC, the effects and benefits could be similar. Although all the benefits mentioned above are based on anecdotal evidence only, science has yet to confirm these health advantages. Therefore, it would be best to consult an expert before using HHC for medicinal purposes.

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